神经元可塑性,学习和记忆

我们作为人类的人在我们的记忆中的总和确定了大程度,是他们亲密回忆,珍贵的事实,有用技能或方便的习惯。此外,我们现在知道允许我们在精神上重演我们个人过去的选定时刻的大脑系统也使我们能够踏上未来的私人心理时间,计划,模拟情景和飞行在想象力的翅膀上。大脑如何完成所有这些?为什么有时我们的记忆欺骗我们将真实与虚构混淆,有时它甚至可能完全失败?例如,为什么有时候我们很快就会摒弃与我们共享的错误信息的验证回忆?我们可以一方面增强记忆力,并防止或改善其他内存缺陷吗?

关于记忆的这些和相关问题是我们部门几个研究小组研究的重点。Together, we tackle memory at multiple levels of analyses, ranging from the basic neuronal machinery that implements synaptic and neuronal plasticity - i.e. elementary building blocks of systems that encode and store memory - to the concerted activity of neuronal circuits that encode and maintain experience-dependent mental representations of the world, to the brain systems that store mental images of events in our life and of places that we visited, and those that control the expression of these recollections at any given point in time. Some of us also investigate the processes and mechanisms that shape the memory of individuals in social milieu. Our multidisciplinary, multi-level experimental approach to neuronal plasticity, learning and memory encompasses a spectrum of cutting-edge methods, ranging from state-of-the-art molecular biology and electrophysiology in animal models to sophisticated psychophysics and behavior, modeling, and the most advanced behavioral protocols and functional neuroimaging of the behaving human brain.

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